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marker cd11c clone 5d11  (Cell Marque)

 
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    Cell Marque marker cd11c clone 5d11
    Marker Cd11c Clone 5d11, supplied by Cell Marque, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/marker cd11c clone 5d11/product/Cell Marque
    Average 90 stars, based on 1 article reviews
    marker cd11c clone 5d11 - by Bioz Stars, 2026-06
    90/100 stars

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    m1 macrophage marker cd11c clone 5d11  (Danaher Inc)
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    <t>CD11c-positive</t> cell infiltration density profiles in the NMIPUC of two selected patients to illustrate different infiltration patterns. Upper panel, patient A with predominant infiltration in the tumor stroma (IDR = 0.074): a representative IHC image area ( left ) and a bar plot ( right ) representing the CD11c cell density distribution across the interface. Lower panel, patient B with relatively higher CD11c cell density in the epithelium (IDR = 0.424). The red dotted line represents the epithelial–stromal interface. A 100 µm measure is added for the reference. Negative distances in the plot represent the stromal aspect of the interface zone. For CD163, CD20, ICOS, and CD8 IHC images in patients A and B, see .
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    marker cd11c clone 5d11  (Cell Marque)
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    <t>CD11c-positive</t> cell infiltration density profiles in the NMIPUC of two selected patients to illustrate different infiltration patterns. Upper panel, patient A with predominant infiltration in the tumor stroma (IDR = 0.074): a representative IHC image area ( left ) and a bar plot ( right ) representing the CD11c cell density distribution across the interface. Lower panel, patient B with relatively higher CD11c cell density in the epithelium (IDR = 0.424). The red dotted line represents the epithelial–stromal interface. A 100 µm measure is added for the reference. Negative distances in the plot represent the stromal aspect of the interface zone. For CD163, CD20, ICOS, and CD8 IHC images in patients A and B, see .
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    marker cd11c clone 5d11 - by Bioz Stars, 2026-06
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    The total number of <t>CD11c+</t> dermal DCs was reduced after laser treatment in cases (C) compared with normal controls (NC) in 5 hpfs (n = 10 patients). *P = 0.0013.
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    monoclonal mouse antibodies to the macrophage/dc marker cd11c clone 5d11  (Novocastra)
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    Image Search Results


    CD11c-positive cell infiltration density profiles in the NMIPUC of two selected patients to illustrate different infiltration patterns. Upper panel, patient A with predominant infiltration in the tumor stroma (IDR = 0.074): a representative IHC image area ( left ) and a bar plot ( right ) representing the CD11c cell density distribution across the interface. Lower panel, patient B with relatively higher CD11c cell density in the epithelium (IDR = 0.424). The red dotted line represents the epithelial–stromal interface. A 100 µm measure is added for the reference. Negative distances in the plot represent the stromal aspect of the interface zone. For CD163, CD20, ICOS, and CD8 IHC images in patients A and B, see .

    Journal: International Journal of Molecular Sciences

    Article Title: Spatial Distribution of Macrophage and Lymphocyte Subtypes within Tumor Microenvironment to Predict Recurrence of Non-Muscle-Invasive Papillary Urothelial Carcinoma after BCG Immunotherapy

    doi: 10.3390/ijms25094776

    Figure Lengend Snippet: CD11c-positive cell infiltration density profiles in the NMIPUC of two selected patients to illustrate different infiltration patterns. Upper panel, patient A with predominant infiltration in the tumor stroma (IDR = 0.074): a representative IHC image area ( left ) and a bar plot ( right ) representing the CD11c cell density distribution across the interface. Lower panel, patient B with relatively higher CD11c cell density in the epithelium (IDR = 0.424). The red dotted line represents the epithelial–stromal interface. A 100 µm measure is added for the reference. Negative distances in the plot represent the stromal aspect of the interface zone. For CD163, CD20, ICOS, and CD8 IHC images in patients A and B, see .

    Article Snippet: We used a CD8 cytotoxic T cell marker (clone C8/144B, Dako, Glostrup, Denmark; dilution 1:100), B cell marker CD20 (clone L26, Dako, Glostrup, Denmark; dilution 1:500), M1 macrophage marker CD11c (clone 5D11, Leica biosystems, Deer Park, NY, USA; dilution 1:100), M2 macrophage marker CD163 (clone MRQ-26, Rocklin, CA, USA; dilution 1:50), and ICOS marker (clone D1K2T, Cell Signaling Technology, Danvers, MA, USA; dilution 1:500) for the identification of specific subpopulations of T cells.

    Techniques:

    The optimal interface zone width for the cell distribution features according to the mean concordance index (CI) in the cross-validation. Immune cell interface density ratio (IDR) across the epithelial–stromal interface.

    Journal: International Journal of Molecular Sciences

    Article Title: Spatial Distribution of Macrophage and Lymphocyte Subtypes within Tumor Microenvironment to Predict Recurrence of Non-Muscle-Invasive Papillary Urothelial Carcinoma after BCG Immunotherapy

    doi: 10.3390/ijms25094776

    Figure Lengend Snippet: The optimal interface zone width for the cell distribution features according to the mean concordance index (CI) in the cross-validation. Immune cell interface density ratio (IDR) across the epithelial–stromal interface.

    Article Snippet: We used a CD8 cytotoxic T cell marker (clone C8/144B, Dako, Glostrup, Denmark; dilution 1:100), B cell marker CD20 (clone L26, Dako, Glostrup, Denmark; dilution 1:500), M1 macrophage marker CD11c (clone 5D11, Leica biosystems, Deer Park, NY, USA; dilution 1:100), M2 macrophage marker CD163 (clone MRQ-26, Rocklin, CA, USA; dilution 1:50), and ICOS marker (clone D1K2T, Cell Signaling Technology, Danvers, MA, USA; dilution 1:500) for the identification of specific subpopulations of T cells.

    Techniques: Marker

    The results of the univariate Cox regression with a p -value lower than 0.2. IDR—immune cell interface density ratio across the epithelial–stromal interface. The stromal and epithelial density corresponds to the specific compartment of the interface zone or total area of the interface zone.

    Journal: International Journal of Molecular Sciences

    Article Title: Spatial Distribution of Macrophage and Lymphocyte Subtypes within Tumor Microenvironment to Predict Recurrence of Non-Muscle-Invasive Papillary Urothelial Carcinoma after BCG Immunotherapy

    doi: 10.3390/ijms25094776

    Figure Lengend Snippet: The results of the univariate Cox regression with a p -value lower than 0.2. IDR—immune cell interface density ratio across the epithelial–stromal interface. The stromal and epithelial density corresponds to the specific compartment of the interface zone or total area of the interface zone.

    Article Snippet: We used a CD8 cytotoxic T cell marker (clone C8/144B, Dako, Glostrup, Denmark; dilution 1:100), B cell marker CD20 (clone L26, Dako, Glostrup, Denmark; dilution 1:500), M1 macrophage marker CD11c (clone 5D11, Leica biosystems, Deer Park, NY, USA; dilution 1:100), M2 macrophage marker CD163 (clone MRQ-26, Rocklin, CA, USA; dilution 1:50), and ICOS marker (clone D1K2T, Cell Signaling Technology, Danvers, MA, USA; dilution 1:500) for the identification of specific subpopulations of T cells.

    Techniques:

    Two Cox regression models with a concordance index > 0.7. IDR—interface density ratio across the epithelial–stromal interface.

    Journal: International Journal of Molecular Sciences

    Article Title: Spatial Distribution of Macrophage and Lymphocyte Subtypes within Tumor Microenvironment to Predict Recurrence of Non-Muscle-Invasive Papillary Urothelial Carcinoma after BCG Immunotherapy

    doi: 10.3390/ijms25094776

    Figure Lengend Snippet: Two Cox regression models with a concordance index > 0.7. IDR—interface density ratio across the epithelial–stromal interface.

    Article Snippet: We used a CD8 cytotoxic T cell marker (clone C8/144B, Dako, Glostrup, Denmark; dilution 1:100), B cell marker CD20 (clone L26, Dako, Glostrup, Denmark; dilution 1:500), M1 macrophage marker CD11c (clone 5D11, Leica biosystems, Deer Park, NY, USA; dilution 1:100), M2 macrophage marker CD163 (clone MRQ-26, Rocklin, CA, USA; dilution 1:50), and ICOS marker (clone D1K2T, Cell Signaling Technology, Danvers, MA, USA; dilution 1:500) for the identification of specific subpopulations of T cells.

    Techniques:

    The results of the multivariate Cox regression with a p -value of individual features lower than 0.05. IDR—immune cell interface density ratio across the epithelial–stromal interface. TLS—the presence of tertiary lymphoid structures.

    Journal: International Journal of Molecular Sciences

    Article Title: Spatial Distribution of Macrophage and Lymphocyte Subtypes within Tumor Microenvironment to Predict Recurrence of Non-Muscle-Invasive Papillary Urothelial Carcinoma after BCG Immunotherapy

    doi: 10.3390/ijms25094776

    Figure Lengend Snippet: The results of the multivariate Cox regression with a p -value of individual features lower than 0.05. IDR—immune cell interface density ratio across the epithelial–stromal interface. TLS—the presence of tertiary lymphoid structures.

    Article Snippet: We used a CD8 cytotoxic T cell marker (clone C8/144B, Dako, Glostrup, Denmark; dilution 1:100), B cell marker CD20 (clone L26, Dako, Glostrup, Denmark; dilution 1:500), M1 macrophage marker CD11c (clone 5D11, Leica biosystems, Deer Park, NY, USA; dilution 1:100), M2 macrophage marker CD163 (clone MRQ-26, Rocklin, CA, USA; dilution 1:50), and ICOS marker (clone D1K2T, Cell Signaling Technology, Danvers, MA, USA; dilution 1:500) for the identification of specific subpopulations of T cells.

    Techniques:

    Kaplan–Maier RFS plots stratified on ( A ) CD11c interface density ratio (IDR) across epithelial–stromal interface, ( B ) CD163 IDR, ( C ) ICOS IDR, ( D ) CD8 IDR, ( E ) density of CD8 cells in epithelial compartment of interface zone, ( F ) presence of tertiary lymphoid structures (TLS), ( G ) presence of tumor in repeated TUR (re-TUR), ( H ) tumor stage, and ( I ) tumor grade. Continuous variables ( A – E ) are stratified according to median value of indicator.

    Journal: International Journal of Molecular Sciences

    Article Title: Spatial Distribution of Macrophage and Lymphocyte Subtypes within Tumor Microenvironment to Predict Recurrence of Non-Muscle-Invasive Papillary Urothelial Carcinoma after BCG Immunotherapy

    doi: 10.3390/ijms25094776

    Figure Lengend Snippet: Kaplan–Maier RFS plots stratified on ( A ) CD11c interface density ratio (IDR) across epithelial–stromal interface, ( B ) CD163 IDR, ( C ) ICOS IDR, ( D ) CD8 IDR, ( E ) density of CD8 cells in epithelial compartment of interface zone, ( F ) presence of tertiary lymphoid structures (TLS), ( G ) presence of tumor in repeated TUR (re-TUR), ( H ) tumor stage, and ( I ) tumor grade. Continuous variables ( A – E ) are stratified according to median value of indicator.

    Article Snippet: We used a CD8 cytotoxic T cell marker (clone C8/144B, Dako, Glostrup, Denmark; dilution 1:100), B cell marker CD20 (clone L26, Dako, Glostrup, Denmark; dilution 1:500), M1 macrophage marker CD11c (clone 5D11, Leica biosystems, Deer Park, NY, USA; dilution 1:100), M2 macrophage marker CD163 (clone MRQ-26, Rocklin, CA, USA; dilution 1:50), and ICOS marker (clone D1K2T, Cell Signaling Technology, Danvers, MA, USA; dilution 1:500) for the identification of specific subpopulations of T cells.

    Techniques:

    Study design chart. Patient selection and tissue selection were followed by IHC analysis and digitization. CD20 slides were then used for TLS identification, and images with excluded TLS areas, together with CD8, ICOS, CD11c, and CD163 images, underwent tissue and cell classification and infiltration analysis for assessment of cell infiltration profiles in epithelium–stroma interface. From resulting cell infiltration profiles, interface zone settings were optimized for all immune cell indicators, which were used for survival analysis to predict RFS.

    Journal: International Journal of Molecular Sciences

    Article Title: Spatial Distribution of Macrophage and Lymphocyte Subtypes within Tumor Microenvironment to Predict Recurrence of Non-Muscle-Invasive Papillary Urothelial Carcinoma after BCG Immunotherapy

    doi: 10.3390/ijms25094776

    Figure Lengend Snippet: Study design chart. Patient selection and tissue selection were followed by IHC analysis and digitization. CD20 slides were then used for TLS identification, and images with excluded TLS areas, together with CD8, ICOS, CD11c, and CD163 images, underwent tissue and cell classification and infiltration analysis for assessment of cell infiltration profiles in epithelium–stroma interface. From resulting cell infiltration profiles, interface zone settings were optimized for all immune cell indicators, which were used for survival analysis to predict RFS.

    Article Snippet: We used a CD8 cytotoxic T cell marker (clone C8/144B, Dako, Glostrup, Denmark; dilution 1:100), B cell marker CD20 (clone L26, Dako, Glostrup, Denmark; dilution 1:500), M1 macrophage marker CD11c (clone 5D11, Leica biosystems, Deer Park, NY, USA; dilution 1:100), M2 macrophage marker CD163 (clone MRQ-26, Rocklin, CA, USA; dilution 1:50), and ICOS marker (clone D1K2T, Cell Signaling Technology, Danvers, MA, USA; dilution 1:500) for the identification of specific subpopulations of T cells.

    Techniques: Selection

    The total number of CD11c+ dermal DCs was reduced after laser treatment in cases (C) compared with normal controls (NC) in 5 hpfs (n = 10 patients). *P = 0.0013.

    Journal: The FASEB Journal

    Article Title: A pilot clinical trial of a near-infrared laser vaccine adjuvant: safety, tolerability, and cutaneous immune cell trafficking

    doi: 10.1096/fj.201801095R

    Figure Lengend Snippet: The total number of CD11c+ dermal DCs was reduced after laser treatment in cases (C) compared with normal controls (NC) in 5 hpfs (n = 10 patients). *P = 0.0013.

    Article Snippet: Sections (5 μm) cut from formalin-fixed, paraffin-embedded tissue blocks were stained for hematoxylin and eosin, CD1a (Langerhans cell marker; clone MTB1, Leica bond ready-to-use anti-human mouse mAb, HIER pH 9.0; Leica Biosystems, Newcastle Upon Tyne, United Kingdom), and CD11c (myeloid DC marker; clone 5D11, Novocastra bond ready-to-use anti-human mouse mAb, 1:200, HIER pH 6.0; Leica Biosystems).

    Techniques:

    Subject 1840-06. Dermal dendritic cells highlighted by CD11c immunohistochemistry are reduced in number after laser treatment (B) as compared with control (A). Original magnification, ×400. The spindle-cell morphology remains unaltered.

    Journal: The FASEB Journal

    Article Title: A pilot clinical trial of a near-infrared laser vaccine adjuvant: safety, tolerability, and cutaneous immune cell trafficking

    doi: 10.1096/fj.201801095R

    Figure Lengend Snippet: Subject 1840-06. Dermal dendritic cells highlighted by CD11c immunohistochemistry are reduced in number after laser treatment (B) as compared with control (A). Original magnification, ×400. The spindle-cell morphology remains unaltered.

    Article Snippet: Sections (5 μm) cut from formalin-fixed, paraffin-embedded tissue blocks were stained for hematoxylin and eosin, CD1a (Langerhans cell marker; clone MTB1, Leica bond ready-to-use anti-human mouse mAb, HIER pH 9.0; Leica Biosystems, Newcastle Upon Tyne, United Kingdom), and CD11c (myeloid DC marker; clone 5D11, Novocastra bond ready-to-use anti-human mouse mAb, 1:200, HIER pH 6.0; Leica Biosystems).

    Techniques: Immunohistochemistry, Control